Description: This study explores how weight loss through diet and exercise affects muscle and major organs in adults with type 2 diabetes. Researchers examined changes in skeletal muscle and organs such as the liver, heart, kidneys, and spleen over two years to better understand how intentional weight loss impacts overall body composition. The goal was to see whether losing weight leads to unhealthy loss of muscle or vital organs, or if these changes occur in a balanced and safe way over time.

Citation: Gallagher, D., Kelley, D. E., Thornton, J., Boxt, L., Pi-Sunyer, X., Lipkin, E., Nyenwe, E., Janumala, I., Heshka, S., & MRI Ancillary Study Group of the Look AHEAD Research Group (2017). Changes in skeletal muscle and organ size after a weight-loss intervention in overweight and obese type 2 diabetic patients. The American journal of clinical nutrition, 105(1), 78–84. https://doi.org/10.3945/ajcn.116.139188

Copyright: © 2017 American Society for Nutrition