Description: Results of an evaluation of how weight gain with glucose-lowering medications may interfere with effective type 2 diabetes management over a 5-year period.

Citation: Wexler, D. J., Garvey, W. T., Ghosh, A., Kazemi, E. J., Krause-Steinrauf, H., Ahmann, A. J., Brown-Friday, J., Casula, S., Cherrington, A. L., Elasy, T. A., Fortmann, S. P., Krakoff, J. A., Mudaliar, S., Tiktin, M., Younes, N., & GRADE Study Research Group (2025). Weight Gain Was Associated With Worsening Glycemia and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes Independent of Diabetes Medication in the GRADE Randomized Controlled Trial. Diabetes care, 48(6), 935–944. https://doi.org/10.2337/dc24-2825