Description: This publication describes a protocol for evaluating the acceptability of using virtual reality to educate emergency department patients about HIV prevention with pre-exposure prophylaxis (PrEP). The study aims to assess whether a VR-based educational intervention is a feasible, engaging, and acceptable way to improve patient knowledge and interest in PrEP among individuals in a high-impact clinical setting. By focusing on patient experience, usability, and implementation potential, the protocol seeks to inform whether immersive digital tools could support HIV prevention outreach and education in emergency care environments.

Citation: Acosta D.R., Aguilar-Hernandez L., Perez G., Guzman-Ruiz I.Y., Castellon J.M., Cruz J., Gutierrez L., Monteon-Garcia P., Torres V.N., Duru O.K., Castellon-Lopez Y. (2026). Evaluating the Acceptability of Using Virtual Reality to Promote Physical Activity Among Latino, Latina, and Latine Adults With Cardiometabolic Risk Factors and Obesity in Underresourced Settings: Protocol for a Qualitative Focus Group Study. JMIR Research Protocols, 15 (e80534). doi: 10.2196/80534