Description: This publication from the Diabetes Prevention Program Research Group examines how lifestyle changes and metformin affect the risk of developing type 2 diabetes in adults with impaired glucose regulation. The findings help estimate individual risk and support personalized prevention strategies.

Citation: Herman WH, Pan Q, Edelstein SL, Mather KJ, Perreault L, Barrett-Connor E, Dabelea DM, Horton E, Kahn SE, Knowler WC, Lorenzo C, Pi-Sunyer X, Venditti E, Ye W; Diabetes Prevention Program Research Group. Impact of Lifestyle and Metformin Interventions on the Risk of Progression to Diabetes and Regression to Normal Glucose Regulation in Overweight or Obese People With Impaired Glucose Regulation. Diabetes Care. 2017 Dec;40(12):1668-1677. doi: 10.2337/dc17-1116. Epub 2017 Oct 11. Erratum in: Diabetes Care. 2018 Apr;41(4):913. doi: 10.2337/dc18-er04. Erratum in: Diabetes Care. 2019 Apr;42(4):701. doi: 10.2337/dc19-er04. PMID: 29021207; PMCID: PMC5711336.