Description: This publications examines hospitalization rates among participants in the GRADE study, comparing glycemia-lowering treatments—insulin glargine, glimepiride, liraglutide, and sitagliptin—added to metformin. It finds hospitalizations were common, with a small but significant reduction in subsequent hospitalization risk for those assigned to liraglutide versus glimepiride, offering insights to guide treatment decisions in similar populations.

Citation: Hsia, D. S., Younes, N., Ghosh, A., Kazemi, E. J., Krause-Steinrauf, H., Buse, J. B., Baker, C., Brown-Friday, J., Diaz, E., Diner, J., Groessl, E. J., Legowski, E. A., Mariash, C. N., Waltje, A. H., Wexler, D. J., Martin, C. L., & GRADE Research Group (2025). Association of Hospitalizations With Randomized Glycemia-Lowering Treatment in GRADE. Diabetes care, 48(7), 1288–1294. https://doi.org/10.2337/dc24-2839

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